When Alexander Fleming discovered penicillin in 1928, when he was able to heal many microbial diseases and save millions of lives, no one suspected that XXI response. A century would become a new challenge.
According to the World Health Organization, today, the resistance to antimicrobials is configured as a real scale of the planet. This bacterium is also evolving and this selection, thanks to these microorganisms, was resistant to the drug originally.
Therefore, it is not enough to develop new drugs, to find a way to make bacteria, selective pressure, resistant, and respond to normal treatment; As a result, they can cause long illnesses to be at greater risk. death
The WHO (WHO) estimates that around 700,000 people per year die worldwide for this reason, if this action does not occur, it will reach 10 millions until 2050. "The change can not wait for the end of the antibiotic period", it was one of the last communications from the world's health organizations.
He also explained that in all medicines and food production, these nations have both abused and systematically abusive medications. There are few antimicrobial substitutes in the research and development phase. Harmonized and immediate measures throughout the world take place during the post-antibiotic period, as common infections can be lethal again.
This concern for the scientific community grows day by day, the high resistance against antibiotic molecules is very high and increases the death and illness of patients. hospitals and some "health care-related infections" (previously called hospital or nosokomial).
The denomination changes from a new paradigm: due to changes in attendance modalities, we have found a variety of patient-assisted procedures, not only in the hospital, but also in day hospitals, geriatric hospitals and home hospitalizations.
Bacteriology, Myology and Clinical Parasitology (SADEBAC) VI. Association of Argentina The experts in the congress explained that the focus of the problem is not only in hospitals and sanatoriums but also in day hospitals, geriatric hospitals and health centers. home hospitalization.
This represents a new global paradigm that connects human, animal and environmental health to each other and cross between three germs.
"These medications are closely linked to the use of medical devices that are not very close to these health infections (IACS), which is why there are currently many more improvised immune systems (transplantation, oncology, etc.) that improperly infect the use of infections "said Jaime Kovensky, a biochemist at Pup, a UBA clinical binder specialist and coordinator of the Subcommittee on Antimicrobial Society Argentina of Bacteriology, Mycology and Clinical Parasitology (SADEBAC).
In this area, one of the issues that most affects the scientific community is the minimum rate for reimbursement for healthcare workers, which does not exceed 30% in our country.
"The biggest problem with cleaning hands is horizontally transmitting bacteria," said Dr. Adriana Sucari, biochemist, President of the Association of Argentine Microbiology (AAM) and SADEBAC President. "Doctors, nurses, kinesiologists, and healthcare workers all carry a bacterial resistant to a patient who does not cleanse the next patient," he added.
There is only one action related to the progress of multi-resistant bacteria alone to reduce IACS. Experts believe that there is much less to minimize the infection rate associated with health care.
"Each medical organization has designed and implemented a surveillance program for the search and prevention standard for carriers of multi-resistant bacteria and the use of contact isolation to prevent horizontal transmission from one patient to another, or in general, in the hands of those in charge and inertia for stethoscopes, thermometers, etc. In addition to the use of standard measures such as gloves, mask, goggles and clothing, it is necessary to manually clean, "he says. Kovensky.
In the last decades, acceleration has been linked to the abuse or abuse of antibiotics that are causing antimicrobial resistance and spreading. "In 2016, antimicrobial resistance began to address the health problem facing the President of the United Nations." For the first time, the state leaders committed themselves to a coordinated and broad strategy. basic antimicrobials resistance (AMR) in human health, animal health and agriculture ", emphasized Kovensky.
Argentina was one of the first to implement national RAM control strategy. Thus, in 2015, the National Antimicrobial Resistance Control Commission (CoNaCRA) was created in collaboration with the Department of Health, Livestock, Agriculture and Fisheries. This committee is made up of both the ministries and the official bodies in the field of matters and the scientific societies involved in the RAM.
According to CoNaCRA experts, antimicrobial resistance problems overcome human health margins and represent a new paradigm that has emerged in recent years around the world. This problem allows human and animal health and environmental health to be the same, and the vector ones are linked to each other.
The term "Health" of the term invented by WHO is "Designing and setting up programs for designing and implementing programs, policies, laws and research, for multi-sector communication and collaboration to achieve better public health outcomes."
"This committee (CoNaCRA) is trying to organize policies and actions to control ADRs, antibiotic-resistant strategies are complex and limit the use of antimicrobials in animal production, especially as a growth promotion and, secondly, no monitoring of antimicrobial resistance to animal origin program, "said Kovensky.
"Another point that CoNaCRA is working hard on is the problem of antimicrobials, especially water," said Sucari. "As regards nutrition, it is worth mentioning the use of antibiotics in the fish industry, since it is often a raw or undercooked meat that is consumed as sushi or ceviche."
Unique use of antibiotics and lack of cooking can lead to increased resistance to antibiotics and bacteria.
With regard to livestock, sheep and pigs, Kovensky has explained that the problem is in intrusively raised animals, and it is limited to areas covered in it. "In our country, birds, especially chicken chickens or chickens, are encouraged to burn and, in a much smaller percentage, livestock farmed livestock feedlot or eat a coral. "
These animals receive antibiotics as promotional growth to obtain bacterial antimicrobial antibiotics. Bacteria, in order to survive in order to survive these substances, make genetic mechanisms that can be transmitted to other bacteria.
Afterwards, when the animals leave their feces, they will have bacterial resistance, they will contaminate the environment that will leave them in the hands of agricultural workers and, when water effluents arrive, they will contaminate the water for irrigation and their fish. For this reason, the expert added that "the problem is not just antibiotics that can be found in animal flesh, but it is the choice of antibiotics that are resistant to the intestinal bacteria."
On the other hand, experts confirmed that it is necessary to work hard to comply with the regulation of sales of human antibiotics. "Antibiotics should be ordered by doctors and the prescription should be presented at a pharmacy," said the non-fulfillment of this regulation, which reaches 80% in the province of Buenos Aires ".
This sale without prescription responds to auto-medication in most cases, because antibiotics are unnecessary, because it is viral and at the same time, the dose or duration of treatment is not appropriate, making a selection of bacteria resistant to infectious focal points or intestinal microbes. "We need to take care of our ecological microbiological flora if we want to advance microbial resistance," they concluded.