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Early birds protect science from depression

Scientists make it easier for people to go to bed and they are more productive in the morning. Their chronotype – that is, the technical name of each sleeping and activity model – is the opposite of the elderly, who work at night and lie down and rise, according to social conventions. A new study, published in Nature Communications on Wednesday, reveals that those who initially wake up are those with genetically-programmed mental illnesses, such as depression or schizophrenia. They say they are better than others.

Of course, each person's genetic condition is conditioned to ease the time or the other. But previous studies have identified only some of the genes associated with chronotropic, and only the studies related to health have found correlations, not causality. According to the new study analyzed by 697,828 people, there are at least 351 genes predisposing to eleven or predatory, more than twenty-five known. When genetic variables share artichokes, the researchers may have a relationship between cause and effect early in the morning and better mental health.

The international research team led by biologists in Exeter (UK) analyzed British genome-based research databases in the British Biobank, as well as data from private companies in the United States and 23 in the United States. Sells personal genetic tests. Each participant previously stated a sleep pattern in a survey. However, scientists were looking for an objective measure of the kronotype, so they included data from 85,760 people, which recorded the activity of the hops with a bracelet.

Genetically predisposed horns that confirm that the study sleeps 25 minutes earlier than the owl in the average. By means of this measure, in the case of the ADN in the morning, compared to 5% of the genes, it was 5% less. The difference between the end of the spectrum and the other seems small, but statistically significant. There was, however, no difference in sleep or quality.

In the mornings, they say they have fewer cases of general well-being and depression and schizophrenia, but researchers have not shown any evidence that early-stage protests against other illnesses, such as diabetes or obesity. "That was amazing," says Dr. Samuel Jones, of the University of Exeter, one of the authors of the research. "Many studies have found that those who have poorer metabolic regulation and, perhaps, the risk of diabetes and obesity, but these studies have a correlation, in genetics, we could infer reason and effect."

Jet lag social

The results of the announcements show that there is a common third factor that affects same-day patients and their illnesses, Jones said. But also, the owl is not common for bad health, but it is not harmful to start from the beginning of the social and labor engagements, as genetics confront you. This creates inequalities in internal biological clocks or social jet lag and has shown negative health effects.

In fact, many of the genes identified in this study regulate circus body clocks, biochemical processes regulating cellular activity. Jones points out that "it can be trained in a certain rhythmic rhythm", especially to keep relaxation and wake up at the same time. "If you are a night person, you will be able to advance a lot of people in the morning," said the researcher. But he adds: "Gene will stay after all because it has an internal clock that makes the owls a bit slower, which is genetic and can not be changed."

The harmful thing is sustained by social work and commitments, because genetics confront us

Maria José Martínez, Coordinator of the Spanish Chronobiology Group (SES), of the Spanish Society of Research Sciences, "can be organized freely by society, everyone can schedule schedules (work, sleep, etc.), because health is a matter of early or afternoon." But Martinez, also in charge of the Kronohealth circadian consultancy, only indicates that the "artificial light is awake during hours and the lights are avoided when going to bed."

Light incidence is an important factor, because it has stopped producing melatonin, a hormone that promotes sleep. It is advisable to advise the body to ask about the body to show light, natural or lamp in the morning before waking up. Indeed, Jones and his colleagues found that some 351 genes related to the chronotomy are indicated in the retinal cells, "the serious ones probably see the light as the carved light", according to the author.

Other identified genes are indicated in the hypothalamus, brain regions that regulate sleep and wakefulness, which are involved in insulin metabolism and are responsible for the treatment of stimulating substances such as contamination and nicotine. All of this emphasizes the intrinsic physiological differences between owls and ferns, but a detailed analysis is needed, how and why this genetic variant of the chronotype affects, and generally, mental health.

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