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Shingles vaccine is mostly mild side effects, says CDC



Shingrix, produced by GlaxoSmithKline and approved by the US Food and Drug Administration in October 2017, is recommended for adults over 50 years of age when it comes to adult-like shingles, which causes a painful eruption. A spinal vaccine is thrown into the upper arm muscle and separates between two and six months.
During the first eight months of post-marketing in Shingrix, Vaccine Adverse Event Reporting System (VAERS) vaccine received a total of 4,381 adverse events; There were 130 of them serious.

When 100,000 doses were distributed, the CDC presented 136 complaints in the system. Approximately 3.2 million doses were distributed by GlaxoSmithKline during the eight months of the CDC.

CDC recommends a new shingles vaccine to replace an older person

Fever, coldness and limb pain and pain, inflammation and breathing shots in the arms were side effects.

However, seven patients were killed within six months of receiving Shingrix for six weeks, the CDC said. The cause of these four deaths was cardiovascular disease (three people had many cardiac risk factors). Two patients with sepsis were immunosuppressed. And the 86-year-old woman died after a fall. v The eighth death of Shingrix's use was also reported to the VAERS, although CDC did not confirm it.

Dr. Elisabeth M. Hesse, the lead author of the report and the person in charge of the doctor, wrote in the Electronic Office of the Immunization Safety CDC: [any of] The deaths reported were related to the vaccine. "

More than 196 patients (4.5% of system reports) said they had received shingles after firing them, although 14 of these patients were vaccinated before vaccination, according to CDC. And more than 1%, or 49 people, died of pain due to shooter; Here are six pre-established cases, the CDC said.

In general, there were 230 vaccination errors, especially if the doctor inserted the vaccine into the skin instead of the muscle, as the manufacturer directs. Likewise, Shingrix will be merged into the two necessary avenues, and in some cases, the provider failed to confuse the content.

Tell all, the CDC found that "non-effective" anti-measles reports on "VAs" were not included in the Shingrix side effects. "Healthcare providers and patients can be reassured", because the early findings of the monitoring tracking system are consistent with clinical trials, CDC wrote. "Unexpected events were strange and unexpected patterns were not detected."

However, in the study of the CDC clinical study, according to Dr. Kathleen Dooling, according to a series of viral diseases, the reactions received by Shingrix were sufficiently alert to 6 patients to avoid normal activities, with four patients suffering from at least three patients. Dooling also said the vaccine protects more than 90% against shingles.

Hesse said that manufacturers should report VAERS to "knowing all the incidents to the vaccine." At the same time, health providers must report some adverse reactions to "strongly insert" vaccinations to any clinically relevant vaccines or events or unexpected events, "he said.

The Rotashield vaccine for reflection was launched, after a study by the VAERS reports on colon obstruction and a verification of these claims.

Administrator disorders, side effects

Dr. Carla Perissinotto, associate and clinical associate at the University of San Francisco University of California Department of Geriatrics, has seen, due to a few patients, the complexity of returning through Medicare.

"You must send the patient bill and then send it to Medicare," said Perissinotto, who had not participated in the new CDC report. The clinics are "administratively" difficult to save Shingrix and then bind Medicare.

"Shingles does not cause" serious misunderstandings "based on" discussions by my colleagues ".

"If the payment structure was easier, we should use it more, which means that many patients do not get it right."

Dr. Alison Moore, UC San Diego Healthcare Geriatrics and Gerontology, told CNN in his email that the vaccine is effective and "recommends prior to a pre-trial version" [shingles] vaccine, Zostavax, "direct CDC-recommended vaccine for adults over 60 years old.

Shingrix is ​​not a live vaccine because "because they have more people," added Moor, who had not participated in the CDC report.

"Patients may have a reaction, mild recipes, redness and warmth and mild pain around the injection site and severe reactions, including fever, cold and disease, like a flu like a flu like a day, said Moor. He first saw reactions With the background, although side effects, it still recommends vaccination, he said, although it warns patients and advises them to reduce the impact of an acetaminophen or ibuprofen drug.

Sean Clements, a spokesman for GlaxoSmithKline, "as a standard practice for all vaccines, wrote in an email message," will continue to control CDC and FDA security.

"Shingrix's seven million doses have been distributed in September 2018, and preliminary data show that about 76% have completed two series of doses," Clements wrote.


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