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The ancient genomes reveal changes in the genetic oriental state of the gorilla

The Grauer's gorilla is being criminally threatened by recently losing its genetic diversity and causing adverse mutations. These results were obtained by an international team that sequenced eleven genomes that were created 100 years ago in relation to gorillas with Eastern genomes and the current genome of individuals. The results are now published Current biology.

Some savages have suffered declines over the past century and scientists are concerned that these imbalances have lost congestion on genetic diversity, inbreeding, and mutation. However, despite the risk of extinction in threatened species, it is difficult to investigate the latest changes in genetic viability. In the new study, scientists from Uppsala University and the Natural History Teachers of Sweden have used species stored in the collections of museums to study gorilla genome Eastern variations over the last 100 years.

"We have found that the genus diversity of Grauer gorilla has fallen sharply in a few generations," says Tom Van der Valk, Ph.D., Uppsala University of Sweden.

The graber gorillas have been found in the Democratic Republic of the Congo and in the last decades, 80 percent less have been due to the destruction of poaching and habitat. Comparisons of historical and modern genomes show that this fall causes loss of growth and genetic variation. This also means that Grauer's gorillas are less capable of coping with future illnesses and environmental changes. In addition, scientists have identified certain mutations, which are probably harmful and had a higher frequency in the 4-5 generations of the past, depending on the size of the population. However, close to the red mountain, scientists did not find significant genetic changes, suggesting that their genetic viability was stable in the last 100 years.

"The latest growth in harmful mutations highlights the need to return to the decline of the ongoing population of Grauer's gorilas," says Dalen at the Swedish Natural History Museum.

Potentially adverse mutations with increased frequency have been found in genes that cause disease resistance and male fertility. Additionally, researchers have identified mutations that cause loss of functions associated with finger development and development, which is why current gorillas sometimes show fusion numbers.

"Our research emphasizes that the issue of historical museums is a special resource to control the latest changes in the genetic state of endangered species," says Katerina Guschanski of Uppsala University.

Interestingly, why Grauer gorillas have been severely affected by mountain gorillas can only deepen their history. While Grauer's gorillas increased during the 5,000 to 10,000 years, the mountain gorillas have been rare for thousands of years. The small size of the long-term population has allowed natural selection to eliminate harmful mutations, the gorilla numbers in the 20th century. They began in the century.


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