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Control of vasculature of tumors according to an overexpressed gene in the vasculature of cancer



Sunday 12/28/2018 5:03:36 PMCET

MADRID, December 28 (EUROPA PRESS) –

The WBU researchers at the University of Geneva (Switzerland) and Amsterdam (Netherlands) have monitored tumor vasculature through a overexpressed gene in the cancer vasculature to develop a new therapeutic approach.

Specifically, Swiss and Dutch researchers have studied the mechanisms of growth of new blood tumors in order to detect the surplus of recipients, which will usually be used as an insulin receptor.

"From a genomic screen, we have found the function of this receptor called insulin receptor (INSR), especially a shorter nonmetal and nonmetallic isoform (INSR-A) in the blood forming process, which allows us to completely block or block tumors growth "said the British Journal of Cancer Magazines.

In his view, discovery "strengths" are the ability to face endothelial tumor, the inner layer of the blood layers in contact with blood and, at the same time, prevent healthy cells. To this end, the researchers compared 11 healthy fibers and the parts of the patient in 11 different tumors, such as kidney, colon or breast.

"When cancer cells are directly attacked, failure is common, because each procedure can lead to a change in tumor behavior, we must be more astute than cancerous cells, intervening with endothelial cells and attacking the vascularization of the tumor, avoiding negligence to prevent tumor attack," the researchers argued. They have not had cancer directly, but they have found a valve that regulates cancer cell turnover.


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