Wednesday , May 18 2022

Genetically modified babies | How did Jiankuik genetically edit babies without stopping anyone? | Technology and science | science


Last year, an unknown Chinese researcher appeared in an exclusive meeting in Berkeley, California, where scientists and labels discussed a technology that shook ground on the ground: A new gene "editing" tool, Strings of DNA that make up the life model.

Young scientists, He was Jiankui, he saw that the potential of this tool was called CRISPRnot only to transform genes, but also to your career.

In visits to the United States, he began searching for pioneers in CRISPR, including Dr. Jennifer Doudna, Berkeley, Stanford University, and Dr. Matthew Porteus of the University of California, as well as great thinkers for his use, such as Stanford, Dr. William Hurlbut.

Last week, scientists were unhappy, unfortunately, they arranged an international conference to help them: first aided by genetically modified childrenIn spite of the clear consensus of scientists, today's generations should not be genetically modified.

The director of the National Institutes of Health of the United States, Francis Collins, said he's an experiment "The most improbable" "He said he was a hero who seemed to be a scientist, because he had exceeded the limits, both scientific and ethical."

But how did nobody stop?

To be honest, scientists claim that there is no way to prevent playing with ADN, regardless of current laws or regulations. CRISPR is cheap and easy to use, why scientists were worried about the technology that had happened like this happened.

And there is a long history in the science and medicine of researchers, and they have begun experiments with disagreements and fears, some of which have led to common practice. In vitro fertilization.

Reproduction genes are prohibited in the United States and almost throughout Europe. In China, the ministry rules that prohibit investigations with the embryo "violate ethical or moral principles."

But it turns out that he did not specifically book the goals. He pursued internationally renowned Stanford and Rice universities, postgraduate work and advice and advice before and after the experiment.

Did you know that the scientists of your plan had to comment or discuss? The answer is not clear.

"It does not fall into the category of legal responsibility, but ethical responsibility," Collins said.

The National Health Commission, the Chinese Academy of Sciences and the University said that he did not know what he was doing and since then he was convicted.

However, three Stanford scientists – former consultant Hurlbut, Porteus and He, Stephen Quake – have had many relationships with him in recent years. Scientists and others knew or had strong suspicions that genetically edited babies were trying to make babies.

Stanford did not answer the interview request.

Quake, a bioengineering teacher, was one of the first pioneers. Each time his former student was in the village, he met him and was told that he was interested in the embryo for baby babies to face the AIDS virus a few years ago, said the teacher.

Hurlbute was convinced that at the beginning of 2017, the creators of CRISPR and Doudna had three encounters with top scientists and labels discussing technology.

Since then, he has returned several times to Stanford and Hurlbut, "he spent some time".

Porteus said he knew he had talked to Hurlbute and that Hurlbute suggested it was a Chinese scientist. In February, he asked him to meet with Porteus and told him he had received permission from the Ethics Committee to the hospital.

"I think I hope it's amazing and I was quite negative," said Porteus. "It was the opposite of its invention, it was a disturbing lie."

Michael Deem, a professor of bioengineering at Rice University and a PhD thesis consultant, said he worked for scientists who came back to China in 2012, who is on the board and "a small stake" of the genes of the Shenzhen Gene genes. The investigator defended the actions he had done with previous animal experiments.

"We have investigated the genetic generations of various genetic generations and the genetic generations of children" and the unwanted effects of other genes, Deem said. When it was present in China, the participant studies allowed it to test the edition of embryonic genes.

There are no international organs to control bioethical norms, and scientific institutions and universities can use other tools.

"If someone breaks the rule, Scientists can isolate you, magazines have not been published, for employees, financiers, "said Hank Greely, Professor of Law and Genetics at Stanford.

Of course, the bad start sometimes ends well.

in In 1978In a press release by Dr. Robert Edwards, he announced for the first time "test tube baby"In the world, Louise Brown.

He later worked The Nobel Prize and in vitro fertilization have helped millions of children.

And this year, Louise Brown – thought of the two children's mother in the old way – turned out to be 40.

(Photo: AP)

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