Sunday , May 16 2021

Identify the first gene associated with gestational diabetes



La Paz (INGEMM) and the scientists of the Andalusian Center for Molecular Biology and Regenerative Medicine have identified diabetes during pregnancy as a risk factor for the first time. The discovery has been published in Diabetes magazine.

Gestational diabetes occurs only during pregnancy and therefore disappears. This disease, through hyperglycemia, can affect the normal development of the fetus and increases the obstetric risk during pregnancy and, such as the macrosomia or the birth weight of the child.

This research opens the door to predict pregnancy hyperglycaemia effectively

Preventing pregnant women from developing gestational diabetes is not known, in Spain, the blood glucose curve in the second quarter to get pregnant women to detect and treat the disease as soon as possible and to reduce the effects of the fetus. and mother

At the beginning of diabetes, pregnancy affects 10% of all pregnant women, both genetic factors and agents, but so far, specific genes were unknown, during which pregnancy caused diabetes.

Over the course of the study, family groups have been gener- atively generational for two or three generational generations of gestational diabetes for generations from generation to generation over generations over generations.

"Our research reveals that the genetic mutation of the PAX8 gene is a risk of diabetes." We knew that the human genome was involved in hypothyroidism, but not in diabetes until now, "explains José Carlos Moreno, who directs the molecular laboratory of the INGEMM thyroid.
Obtain a predicted diagnosis

This study opens the door to better understanding the genetic factors that cause the risk of diabetes, leading to early and effective diagnosis of pregnancy hyperglycaemia.

Families of these mutations may also be useful for avoiding the onset of older children with 2-year-old diabetes, as the diabetes gestapo may have an early manifestation, as a sign of permanent diabetes as the "sentinel" sign as an adult age


Source link