Tuesday , March 21 2023

Mexican fish capable of healing the heart provides hope for patients with heart disease


University of Oxford scientists have researched Mexican fish that are able to recover their heart and find it The extraordinary potential that allows the gene to be present in humans. The results of the new study, published in the journal Cell Reports, offer positive changes in the life of the patients with heart attack. Researchers say.

In order to reach this conclusion, a group of scientists led by Mathilda Mommersteeg learned two types of Tetra Mexican fish. du Astyanax mexicanus, who lives in the rivers And it shows a beautiful color, heals your heart while it is the second subspecies populate the cave waters It's called Pachón "Tetra blind" & # 39;Not only has the color and sight lost, the features that are not served in the darkness of the cave, but it does not have the ability to recover the heart tissue.

In research, researchers They compared genetic profiles of two types of tetra-fishes and have identified two genotypes that have the ability to regenerate the damaged heart tissues.

Then, if the behavior of these genes was compared to the Tetra River and the subsequent tetra-blind followers of heart disease, scientists only discovered the first gene that increased the activity of the two genes. Lrrc10 (also in humans) and caveolin.

Amongst the study's previous mice, lrrc10 also has a heart condition called cardiomyopathy, and the heart becomes excessive and the blood does not have enough blood. The results of subsequent studies were suggested Lrrc10 is a fundamental task in the contraction and spread of heart cells.

To confirm that this gene is part of the regeneration of the damaged tissue of the heart, the new study researchers have turned zebrafish into fishes, other species like fresh water, tetra-like fish, and regenerative capacity of the heart. if necessary Scientists have blocked the expression of lrrc10 gene zebra fibers so they can not effectively deal with heart damage.

In the future, the research team hopes to use more information on the mechanisms of tissue recovery mechanisms and the knowledge of people with problems of this organ, such as heart failure.

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