Wednesday , October 20 2021

Nanoparticles to restore teeth and bones



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CSIC develops a method that acts as a reactive precursor of a crystalline compound deposited in the skin teeth

CSIC / DICYT The Research Council of the Scientific Research Council (CSIC) and Consiglio Nazionale delle Ricerche (CNR) have developed nanoparticles to restore teeth and bones, taking into account the reagent of a glass composite in the tooth complement. These particles have a great potential to treat toothpastes, gum, goat's water and varnish fluorine, to treat teeth sensitivity and enamel erosion. The inventory is sponsored by a European patent and licensed to Kalichem Italia srl. Nanoparticles will be part of the internationally recognized brand's oral hygiene product.

In the field of crystallographic research, nanoparticles have been investigated by the Institute of Earth Sciences of Andalusia (CSIC Mixed Center and University of Granada) and the CNR Institute of Science and Technology Materials Certifications.

"Most components of bone and mineral teeth are crystalline calcium phosphate forms," ​​explains Jaime Gómez Morales. "The newly developed nanoparticles make up an amorphous calcium phosphate (AKP), which translates into crystalline forms that resonate enamel and dentino and strengthen the bones," he added. "In addition, in nanoparticles of 30 and 80 nanometers, the amorphous phosphate is fluorinated with phosphate and carbonate and is covered with citrus molecules," said Gómez Morales.

The process for the preparation of these nanoparticles is based on the processes of nature formation and is low cost: at the ambient temperature and at the economic outlets, it requires a single reaction step, so that it respects the environment.

Other interesting features of nanoparticles are biodegradable, bioscience and excellent biocompatibility, evidenced by cell test. in vitroIn this way, they will also present potential applications for drug nano-packaging. Its pH-dependent solubility controls the drug in a controlled manner.

The Nanoparticle Patent, already in Spain and the United States, has opened its doors to Brazil, China, South Korea, Japan, Russia and the European Patent Office in the international arena.

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