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The dream is not the same when it comes to cleaning the brain

Posted on 02/28/2019 at 8:05:34CET

MADRID, February 28 (EUROPA PRESS) –

New research shows how deep sleep can affect the brain's waste and the effective removal of toxic proteins. In fact, since sleep is often more elated and more vulnerable, research is reinforcing and potentially expanding the risk of aging, sleep, and the risk of Alzheimer's disease.

"Sleep is essential in the function of brain wasting and this study shows the dream more, better"said CEO of Maiken Nedergaard, director of the Center for Translation of Neuromedicine Translator, at the University of Rochester Medical Center (URMC), New York, United States." As they show more and more clearly, sleep quality or sleep deprivation prevents Alzheimer's disease and dementia, "he added.

The research published in Science Advancement indicates that there is no slow and stable heart and cardiopulmonate activity related to deep sleep REM, due to the fact that the function of the glyph system is the only process for the elimination of cerebral debris. The discovery also explains why some forms of anesthesia affect older cognitive decline.

Unknown unknown glyph system Nedergaard and his colleagues first described for the first time. At that time, scientists did not fully understand how the brain closes and maintains its ecosystem, deleting waste. The research shows that the blood vessels and pumps develop piping systems that develop through the development of brain fluid fluid (CSF) to eliminate waste. Later, the work worked on this system especially when we sleep.


The accumulation of toxic proteins, such as amyloid beta and tau in the brain are associated with Alzheimer's disease, researchers have specified that the main determinant of the disease is the main determinant of the disease in the deterioration of the glutamic system. This is a clinical observation that shows the interaction between sleep deprivation and Alzheimer's disease.

At this moment, Scientists have experimented with anesthetized anesthetics with six anesthetic regimens. While the animals were under anesthesia, the researchers monitored the brain's electrical activity, cardiovascular activity and the brain through CSF emission. The group replicated combinations of drugs with ketamine and xylazine (K / X) with a slow and stable electrical brain activity and a heart attack that was not associated with REM sleep. In addition, electric activity of the rodents brainwashing K / X was suitable for the function of the glucose system.

"Neural activity in wave wave synchronized slow sleep, specifically the activation patterns that move from the previous section of the brain, relates to GLF flow," says the first researcher, Lauren Hablitz, associate researcher at the Nedergaard laboratory. "It is a chemistry used to activate neurons, that is, the process of osmosis that helps the ions to flow through the brain tissue."

The study raises important clinical questions. In addition, it links sleep, aging and Alzheimer's disease. It is known to be older, it is harder to have REM continually not sleeping, and the study admits the importance of sleep deprivation to get the proper functioning of the glyph system.

The study also shows that the glyphic system can be manipulated to improve sleep, such as possible clinical approaches, such as sleep treatment or other methods to improve sleep quality, depending on the populations at risk.

Besides, Some compounds used in the study were anesthetics used in clinical diversityStudy also illuminates the cognitive illnesses of older illnesses, which often suggest after surgery, the class of medications that can be used to prevent this phenomenon. An analysis of anesthesia-resistant brain activity activity reduced glyphosic activity.

"Cognitive problems after anesthesia and surgery are a serious problem," says Tuomas Lilius, researcher at the Center for Translational Neuromedicine at the University of Copenhagen in Denmark. Significant percentage of elderly patients have a period of delusional surgery after or a new or increased cognitive discharge increases. "

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