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They create mini placentas to study diseases during pregnancy



The Lara Press | EFE.- A group of researchers from the University of Cambridge published this Wednesday on Nature magazine a study on an innovative technique to analyze the development of human placenta through laboratory crops, which will increase awareness about diseases that arise during pregnancy.

The process consists in the creation of organoids, that is, miniaturized models of an organ that develop in the laboratory and that allow a better understanding of how a placenta develops during pregnancy.

In this way, several of the disorders that occur during this process can be studied, such as pre-eclampsia, restriction of growth and fetal death, which are due to abnormal fetal growth within the placenta during the first trimester.

Until now the knowledge of the human placenta was limited due to the lack of functional models created in the laboratory with which to be able to experience, so the development of organoids will allow to expand the inquiries in this field.

Scientists, led by professor at the University of Cambridge, Ashley Moffett, used the long-term generation of organoid cultures created from trophoblastic cells that are removed from the placenta during the first trimester, between six and nine weeks of gestation

The crops grew rapidly and developed three-dimensional organoidal structures during the first fifteen days, and even three randomly selected crops continued to grow healthy after one year.

These organoids will also allow you to study the physiological, metabolic and hormonal changes that occur during pregnancy.

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